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viruses

  • Open Access
    Comparative Genomic Analysis of Rapidly Evolving SARS-CoV-2 Reveals Mosaic Pattern of Phylogeographical Distribution
    Research Article | Ecological and Evolutionary Science
    Comparative Genomic Analysis of Rapidly Evolving SARS-CoV-2 Reveals Mosaic Pattern of Phylogeographical Distribution

    The COVID-19 pandemic continues to storm the world, with over 6.5 million cases worldwide. The severity of the disease varies with the territories and is mainly influenced by population density and age factor. In this study, we analyzed the transmission pattern of 95 SARS-CoV-2 genomes isolated from 11 different countries. Our study also revealed several nonsynonymous mutations in ORF1b and S-proteins and the impact on their structural...

    Roshan Kumar, Helianthous Verma, Nirjara Singhvi, Utkarsh Sood, Vipin Gupta, Mona Singh, Rashmi Kumari, Princy Hira, Shekhar Nagar, Chandni Talwar, Namita Nayyar, Shailly Anand, Charu Dogra Rawat, Mansi Verma, Ram Krishan Negi, Yogendra Singh, Rup Lal
  • Open Access
    Local Action with Global Impact: Highly Similar Infection Patterns of Human Viruses and Bacteriophages
    Editor's Pick Research Article | Host-Microbe Biology
    Local Action with Global Impact: Highly Similar Infection Patterns of Human Viruses and Bacteriophages

    While host-virus interaction interfaces have been previously investigated, relatively little is known about the indirect interactions of pathogen and host proteins required for viral infection and host cell function. Therefore, we investigated the topological relationships of human and bacterial viruses and how they interact with their hosts. We focused on those host proteins that are directly targeted by viruses, those that are...

    Rachelle Mariano, Sawsan Khuri, Peter Uetz, Stefan Wuchty
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