microbial interactions
Special Issue Perspective | Host-Microbe BiologyConsidering the Other Half of the Gut Microbiome: BacteriophagesBacteriophages, viruses specific to bacteria, regulate bacterial communities in all known microbial systems. My research aims to determine how they interact with the trillions of bacteria found in the human gut.
Special Issue Perspective | Novel Systems Biology TechniquesStrengthening Insights in Microbial Ecological Networks from Theory to ApplicationsNetworks encode the interactions between the components in complex systems and play an essential role in understanding complex systems. Microbial ecological networks provide a system-level insight for comprehensively understanding complex microbial interactions, which play important roles in microbial community assembly.
Editor's Pick Research Article | Applied and Environmental ScienceA Phylogenetic and Functional Perspective on Volatile Organic Compound Production by ActinobacteriaSoil microbes produce a diverse array of natural products, including volatile organic compounds (VOCs). Volatile compounds are important molecules in soil habitats, where they mediate interactions between bacteria, fungi, insects, plants, and animals. We measured the VOCs produced by a broad diversity of soil- and dust-dwelling Actinobacteria in vitro. We detected a total of 126 unique volatile compounds, and each strain...
Research Article | Ecological and Evolutionary ScienceMachine Learning Reveals Missing Edges and Putative Interaction Mechanisms in Microbial Ecosystem NetworksDifferent organisms in a microbial community may drastically affect each other’s growth phenotypes, significantly affecting the community dynamics, with important implications for human and environmental health. Novel culturing methods and the decreasing costs of sequencing will gradually enable high-throughput measurements of pairwise interactions in systematic coculturing studies. However, a thorough characterization of all...
Research Article | Ecological and Evolutionary ScienceIndirect Interspecies Regulation: Transcriptional and Physiological Responses of a Cyanobacterium to Heterotrophic PartnershipThis study elucidates how a cyanobacterial primary producer acclimates to heterotrophic partnership by modulating the expression levels of key metabolic genes. Heterotrophic bacteria can indirectly regulate the physiology of the photoautotrophic primary producers, resulting in physiological changes identified here, such as increased intracellular ROS. Some of the interactions inferred from this model system represent putative principles...