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intestinal colonization

  • Open Access
    Identification of Pathogenicity-Associated Loci in <span class="named-content genus-species" id="named-content-1">Klebsiella pneumoniae</span> from Hospitalized Patients
    Research Article | Host-Microbe Biology
    Identification of Pathogenicity-Associated Loci in Klebsiella pneumoniae from Hospitalized Patients

    Klebsiella pneumoniae is a common cause of infections in the health care setting. This work supports a paradigm for K. pneumoniae pathogenesis where the accessory genome, composed of genes present in some but not all isolates, influences whether a strain causes infection or asymptomatic colonization...

    Rebekah M. Martin, Jie Cao, Weisheng Wu, Lili Zhao, David M. Manthei, Ali Pirani, Evan Snitkin, Preeti N. Malani, Krishna Rao, Michael A. Bachman
  • Open Access
    Seven Billion Microcosms: Evolution within Human Microbiomes
    Special Issue Perspective | Ecological and Evolutionary Science
    Seven Billion Microcosms: Evolution within Human Microbiomes

    Rational microbiome-based therapies may one day treat a wide range of diseases and promote wellness. Yet, we are still limited in our abilities to employ such therapies and to predict which bacterial strains have the potential to stably colonize a person.

    Tami D. Lieberman
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