intestinal colonization
- Research Article | Host-Microbe BiologyIdentification of Pathogenicity-Associated Loci in Klebsiella pneumoniae from Hospitalized Patients
Klebsiella pneumoniae is a common cause of infections in the health care setting. This work supports a paradigm for K. pneumoniae pathogenesis where the accessory genome, composed of genes present in some but not all isolates, influences whether a strain causes infection or asymptomatic colonization...
- Special Issue Perspective | Ecological and Evolutionary ScienceSeven Billion Microcosms: Evolution within Human Microbiomes
Rational microbiome-based therapies may one day treat a wide range of diseases and promote wellness. Yet, we are still limited in our abilities to employ such therapies and to predict which bacterial strains have the potential to stably colonize a person.