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International Space Station

  • Open Access
    Genomic Characterization and Virulence Potential of Two <em>Fusarium oxysporum</em> Isolates Cultured from the International Space Station
    Research Article | Molecular Biology and Physiology
    Genomic Characterization and Virulence Potential of Two Fusarium oxysporum Isolates Cultured from the International Space Station

    This is the first study to isolate and characterize F. oxysporum isolates from a built environment, as well as one that has been exposed to space. The characterization and analysis of these two genomes may have important implications for the medical, agricultural, and food industries as well as for the health of the crew who coinhabit the ISS with these strains.

    ...
    Camilla Urbaniak, Peter van Dam, Alexander Zaborin, Olga Zaborina, Jack A. Gilbert, Tamas Torok, Clay C. C. Wang, Kasthuri Venkateswaran
  • Open Access
    Pangenomic Approach To Understanding Microbial Adaptations within a Model Built Environment, the International Space Station, Relative to Human Hosts and Soil
    Editor's Pick Research Article | Ecological and Evolutionary Science
    Pangenomic Approach To Understanding Microbial Adaptations within a Model Built Environment, the International Space Station, Relative to Human Hosts and Soil

    The built environment contains a variety of microorganisms, some of which pose critical human health risks (e.g., hospital-acquired infection, antibiotic resistance dissemination). We uncovered a combination of complex biological functions that may play a role in bacterial survival under the presumed selective pressures in a model built environment—the International Space Station—by using an approach to compare pangenomes of bacterial...

    Ryan A. Blaustein, Alexander G. McFarland, Sarah Ben Maamar, Alberto Lopez, Sarah Castro-Wallace, Erica M. Hartmann
  • Open Access
    Characterization of <span class="named-content genus-species" id="named-content-1">Aspergillus niger</span> Isolated from the International Space Station
    Research Article | Molecular Biology and Physiology
    Characterization of Aspergillus niger Isolated from the International Space Station

    A thorough understanding of how fungi respond and adapt to the various stimuli encountered during spaceflight presents many economic benefits and is imperative for the health of crew. As A. niger is a predominant ISS isolate frequently detected in built environments, studies of A. niger strains...

    Jillian Romsdahl, Adriana Blachowicz, Abby J. Chiang, Nitin Singh, Jason E. Stajich, Markus Kalkum, Kasthuri Venkateswaran, Clay C. C. Wang
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