International Space Station
Research Article | Molecular Biology and PhysiologyGenomic Characterization and Virulence Potential of Two Fusarium oxysporum Isolates Cultured from the International Space StationThis is the first study to isolate and characterize F. oxysporum isolates from a built environment, as well as one that has been exposed to space. The characterization and analysis of these two genomes may have important implications for the medical, agricultural, and food industries as well as for the health of the crew who coinhabit the ISS with these strains.
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Editor's Pick Research Article | Ecological and Evolutionary SciencePangenomic Approach To Understanding Microbial Adaptations within a Model Built Environment, the International Space Station, Relative to Human Hosts and SoilThe built environment contains a variety of microorganisms, some of which pose critical human health risks (e.g., hospital-acquired infection, antibiotic resistance dissemination). We uncovered a combination of complex biological functions that may play a role in bacterial survival under the presumed selective pressures in a model built environment—the International Space Station—by using an approach to compare pangenomes of bacterial...
Research Article | Molecular Biology and PhysiologyCharacterization of Aspergillus niger Isolated from the International Space StationA thorough understanding of how fungi respond and adapt to the various stimuli encountered during spaceflight presents many economic benefits and is imperative for the health of crew. As A. niger is a predominant ISS isolate frequently detected in built environments, studies of A. niger strains...