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hepatocellular carcinoma

  • Open Access
    Alterations in the Gut Microbiome in the Progression of Cirrhosis to Hepatocellular Carcinoma
    Research Article | Host-Microbe Biology
    Alterations in the Gut Microbiome in the Progression of Cirrhosis to Hepatocellular Carcinoma

    Development of hepatocellular carcinoma in patients with cirrhosis is associated with alterations in intestinal microbiota, including an escalation of dysbiosis and reduced bacterial richness. This study demonstrates that reduced bacterial richness and dysbiosis escalate with the progression of cirrhosis from compensated to decompensated cirrhosis and to HCC-associated cirrhosis (HCC-cirrhosis). Moreover, we report for the first time...

    Yelena Lapidot, Amnon Amir, Rita Nosenko, Atara Uzan-Yulzari, Ella Veitsman, Oranit Cohen-Ezra, Yana Davidov, Peretz Weiss, Tanya Bradichevski, Shlomo Segev, Omry Koren, Michal Safran, Ziv Ben-Ari
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