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glutamate

  • Open Access
    Alterations in Gut Glutamate Metabolism Associated with Changes in Gut Microbiota Composition in Children with Autism Spectrum Disorder
    Research Article | Host-Microbe Biology
    Alterations in Gut Glutamate Metabolism Associated with Changes in Gut Microbiota Composition in Children with Autism Spectrum Disorder

    Multiple lines of evidence suggest that the gut microbiota may play an important role in the pathogenesis of ASD, but the specific mechanism is still unclear. Through a comprehensive gut metagenomic and metabolome study of children with ASD, alterations in gut metabolite composition were found in children with ASD, and these alterations were linked to changes in gut microbiota composition. This may give us a deeper understanding of the...

    Mingbang Wang, Jing Wan, Han Rong, Fusheng He, Hui Wang, Jiaxiu Zhou, Chunquan Cai, Yan Wang, Ruihuan Xu, Zhaoqing Yin, Wenhao Zhou
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