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evaluation

  • Open Access
    Defining and Evaluating Microbial Contributions to Metabolite Variation in Microbiome-Metabolome Association Studies
    Research Article | Novel Systems Biology Techniques
    Defining and Evaluating Microbial Contributions to Metabolite Variation in Microbiome-Metabolome Association Studies

    Identifying the key microbial taxa responsible for metabolic differences between microbiomes is an important step toward understanding and manipulating microbiome metabolism. To achieve this goal, researchers commonly conduct microbiome-metabolome association studies, comprehensively measuring both the composition of species and the concentration of metabolites across a set of microbial community samples and then testing for...

    Cecilia Noecker, Hsuan-Chao Chiu, Colin P. McNally, Elhanan Borenstein
  • Open Access
    Strengthening Insights in Microbial Ecological Networks from Theory to Applications
    Special Issue Perspective | Novel Systems Biology Techniques
    Strengthening Insights in Microbial Ecological Networks from Theory to Applications

    Networks encode the interactions between the components in complex systems and play an essential role in understanding complex systems. Microbial ecological networks provide a system-level insight for comprehensively understanding complex microbial interactions, which play important roles in microbial community assembly.

    Xiaofei Lv, Kankan Zhao, Ran Xue, Yuanhui Liu, Jianming Xu, Bin Ma
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