biosynthetic gene clusters
ObservationPhylogenetic Distribution of Secondary Metabolites in the Bacillus subtilis Species ComplexMembers of the B. subtilis species complex are commonly recognized producers of secondary metabolites, among those, the production of antifungals, which makes them promising biocontrol strains. While there are studies examining the distribution of well-known secondary metabolites in Bacilli, intraspecies clade-specific distribution has not been systematically...
Research Article | Ecological and Evolutionary ScienceGenomic and Chemical Diversity of Bacillus subtilis Secondary Metabolites against Plant Pathogenic FungiSecondary or specialized metabolites with antimicrobial activities define the biocontrol properties of microorganisms. Members of the Bacillus genus produce a plethora of secondary metabolites, of which nonribosomally produced lipopeptides in particular display strong antifungal activity.
Opinion/Hypothesis | Therapeutics and PreventionMetaMed: Linking Microbiota Functions with Medicine TherapeuticsUnderstanding how the human microbiome affects human health has consequences for treating disease and minimizing unwanted side effects in clinical research.
Research Article | Host-Microbe BiologyExploration of the Biosynthetic Potential of the Populus MicrobiomeThe plant root microbiome is one of the most diverse and abundant biological communities known. Plant-associated bacteria can have a profound effect on plant growth and development, and especially on protection from disease and environmental stress. These organisms are also known to be a rich source of antibiotic and antifungal drugs. In order to better understand the ways bacterial communities influence plant health, we evaluated the...