bacitracin
- Research Article | Molecular Biology and PhysiologyFrom Modules to Networks: a Systems-Level Analysis of the Bacitracin Stress Response in Bacillus subtilis
Antibiotic resistance poses a major threat to global health, and systematic studies to understand the underlying resistance mechanisms are urgently needed. Although significant progress has been made in deciphering the mechanistic basis of individual resistance determinants, many bacterial species rely on the induction of a whole battery of resistance modules, and the complex regulatory networks controlling these modules in response to...
- Research Article | Ecological and Evolutionary ScienceLoss of Bacitracin Resistance Due to a Large Genomic Deletion among Bacillus anthracis Strains
Anthrax is caused by Bacillus anthracis, an endospore-forming soil bacterium. The genetic diversity of B. anthracis is known to be low compared with that of Bacillus species. In this study, we performed whole-genome sequencing of...