16S rRNA amplicon
Research Article | Host-Microbe BiologyAge- and Sex-Dependent Patterns of Gut Microbial Diversity in Human AdultsMicroorganisms in the human gut play a role in health and disease, and in adults higher gut biodiversity has been linked to better health. Since gut microorganisms may be pivotal in the development of microbial therapies, understanding the factors that shape gut biodiversity is of utmost interest. We performed large-scale analyses of the relationship of age and sex to gut bacterial diversity in adult cohorts from four geographic regions...
Research Article | Novel Systems Biology TechniquesKatharoSeq Enables High-Throughput Microbiome Analysis from Low-Biomass SamplesVarious indoor, outdoor, and host-associated environments contain small quantities of microbial biomass and represent a niche that is often understudied because of technical constraints. Many studies that attempt to evaluate these low-biomass microbiome samples are riddled with erroneous results that are typically false positive signals obtained during the sampling process. We have investigated various low-biomass kits and methods to...