TABLE 4

COG categories and functional descriptions of genes mutated in at least two mutants of E. coli and K. pneumoniae

TABLE 4
  • a Gene accession numbers are indicated for E. coli ATCC 25922 and K. pneumoniae ATCC 13883. The number of mutants in which the genes were found mutated is indicated within parentheses.

  • b Gene designations in bold represent orthologues sharing at least 70% sequence identity at the protein level.

  • c Gene designations in italics represent genes that have been functionally tested for their role in resistance to IMP by individual transformation in E. coli ATCC 25922 WT (see Table 5).