TABLE 4

Four putative Acr-Aca loci from four genomes with self-targeting spacers

ParameterData for species namea:
Pseudoramibacter
alactolyticus
ATCC 23263
Bacteroides
salyersiae strain
2789STDY5608871
Geoalkalibacter
subterraneus
Clostridioides
difficile isolate
VL_0239
RefSeq genome IDGCF_000185505GCF_001405695GCF_000827125GCF_900013625
Self-targeting
CRISPR-Cas subtype
III-AIII-BIV-AV-U4
Acr-Aca locus on the same
contig as spacer target
WP_006597765.1 to
WP_006597766.1
WP_025819230.1 to
WP_005928638.1
WP_040200104.1 to
WP_040200103.1
WP_003438035.1 to
WP_003438037.1
Aca/HTH protein IDWP_006597766.1WP_005928638.1WP_040200103.1WP_003438035.1
Aca is antitoxin hitYesYesYesYes
Acr protein IDWP_006597765.1WP_025819230.1WP_040200104.1WP_003438037.1
Acr is toxin hitNoYesYesNo
No. of other
candidate Acr-Aca loci
0004
Other CRISPR-Cas system(s)I-C, II-ANoI-CI-B
  • a Details about these loci can be found in Data Set S3.