TABLE 1

Differentially regulated operons after induction of test fermentations expressing active CimA3.7 and producing citramalatea

Gene or
operon
FunctionMaximum
fold change
Direction of
regulation
mdtEF-tolCMultidrug resistance
efflux transporter
4.6Up
malEFGMaltose transport3.1Down
gadBCAcid resistance2.3Up
treBCEnzIITre PTS; trehalase
6-P hydrolase
2.3Down
entCABEHEnterobactin synthesis2.3Up
hdeAB-yhiDAcid resistance2.1Up
alaEl-Alanine export2.0Up
  • a Fold change is for the first gene in the operon unless indicated otherwise by boldface type.