TABLE 2

Selected PA14 genes differentially expressed in blood from SBPs and TPs

LocusGeneaProductFold changeb
SBPTP
PA14_02570mdcCMalonate decarboxylase subunit delta11.636.00
PA14_02550mdcAMalonate decarboxylase subunit alpha12.135.86
PA14_02560PA14_02560Triphosphoribosyl-dephospho-CoA synthase20.734.20
PA14_02590mdcEMalonate decarboxylase subunit gamma8.544.00
PA14_02580mdcDMalonate decarboxylase subunit beta13.173.00
PA14_33500pvdHDiaminobutyrate–2-oxoglutarate aminotransferase−4.61−2.35
PA14_33680fpvAFerripyoverdine receptor−4.34−1.56
PA14_33690pvdEPyoverdine biosynthesis protein PvdE−2.36−2.11
PA14_33700pvdFPyoverdine synthetase F−4.94−1.89
PA14_33710pvdOProtein PvdO−4.71−1.83
PA14_33720pvdNProtein PvdN−2.45−1.72
PA14_33810pvdAl-Ornithine N5-oxygenase−3.81−2.27
PA14_46970ansBGlutaminase-asparaginase−5.99−2.29
PA14_62130ilvCKetol-acid reductoisomerase−2.77−1.54
PA14_62150ilvHAcetolactate synthase 3 regulatory subunit−2.35−1.70
  • a Genes specifically discussed in the text; for the complete list of 100 genes, see Table S4.

  • b Upregulation (boldface) and downregulation (italics) of gene expression in PA14 grown in blood from severely burned patients (SBPs) or TPs compared to levels for healthy volunteers.