TABLE 2

Occurrence of adverse events during the probiotic and placebo intervention perioda

SymptomSeverityNo. of events occurring during
administration of:
P value
Probiotic (n = 28)Placebo (n = 28)
Abdominal painMild110.157
Moderate01
Allergic reactionMild011.000
ArthralgiaMild101.000
DiarrheaMild130.577
Moderate11
Gastritis and enterocolitisModerate111.000
GI disorders—other, loose stoolsMild451.000
Laryngeal inflammationModerate011.000
MyositisMild011.000
ToothacheMild011.000
  • a Values were compared with McNemar tests when only one grade of severity was reported (mild or moderate) and with Wilcoxon signed-rank tests when two grades were reported. GI, gastrointestinal; n, number of subjects.