TABLE 1

Incidence of lesions in liver and colon

Animal and lesion parameterValuea
ColonLiver
Inflammatory cells—lamina propriaLymphocytes—
laminapropria
Hydropic degenerationFat depositionLymphocyte infiltrationInflammatory cells—periportal region
Control pups
    Grade 01083689
    Grade 124121
    Grade 222
    Grade 311
    Grades 1–30b27421b
BPA pups
    Grade 0233882
    Grade 154103
    Grade 2303
    Grade 310
    Grades 1–35b45006b
  • a H&E-stained sections were scored based on a grade of 0 to 3 (0 = no lesions; 3 = severe lesions).

  • b Data were significant at a P value of <0.05 (Fisher exact test).