TABLE 1

Predicted metagenome contributions of phylotypes (at the family level) to genes encoding key enzymes involved in the production and consumption of butyrate, acetate, succinate, and lactate

Enzyme (no.) and phylotypeContribution of phylotype (%)a
BatchContinuous
4-Hydroxybutyryl-CoA dehydratase (17)
    Ruminococcaceae095 ± 5
    Clostridiaceae1003 ± 1
Butyrate kinase (7)
    Prevotellaceae1592 ± 7
    Ruminococcaceae03 ± 0
    Clostridiaceae440
    Lachnospiraceae11 ± 0
    Lactobacillaceae350
Acetate kinase (9)
    Prevotellaceae1634 ± 21
    Ruminococcaceae043 ± 18
    Clostridiaceae571 ± 1
    Lachnospiraceae127 ± 6
    Actinomycetaceae012 ± 4
Fumarate reductase (12)
    Clostridiaceae121 ± 1
    Lactobacillaceae252 ± 1
    Alcaligenaceae5196 ± 2
Succinyl-CoA synthetase (13)
    Prevotellaceae2061 ± 16
    Actinomycetaceae020 ± 17
    Bifidobacteriaceae671 ± 0
Lactate dehydrogenase (18)
    Ruminococcaceae057 ± 1
    Lactobacillaceae676 ± 1
    Actinomycetaceae07 ± 6
  • a Average of three samples ± standard deviation.