TABLE 2

Genes most frequently downregulated following RSV infectiona

Weighted scoreGene(s)
9CLC
6NDUFS1, PFDN5
5RTN1, CAT, FCER1A, TSPAN8, ALOX15, GPR56, KLRB1
4XRCC5, LMNA, UBD, CCT3, HSPA8, GARS
  • a Genes were collated from multiple studies of RSV. A cutoff of a 2-fold decrease in expression was used when available. Genes were weighted as follows on the basis of the studies from which they were collated: human genetic studies, 4; human in vivo microarray studies, 3; human in vitro microarray studies, 2; mouse studies, 1. After weighting, genes were analyzed for multiple hits by a custom Perl script.