↵a The rhythmicity was assessed by cosinor analysis, and

*P*< 0.05 indicated a significant rhythm; ns means the difference was nonsignificant (*P*> 0.05). The model can be written according to the equation f(x) = A + B cos [2 π(x + C)/24], with f(x) indicating relative expression levels of target genes, x indicating the time of sampling (h), A indicating the mean value of the cosine curve (midline estimating statistic of rhythm [mesor]), B indicating the amplitude of the curve (half of the sinusoid), and C indicating the acrophase (h).