High-Resolution Longitudinal Dynamics of the Cystic Fibrosis Sputum Microbiome and Metabolome through Antibiotic Therapy

DOI: 10.1128/mSystems.00292-20

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^aDepartment of Biochemistry and Molecular Biology, Michigan State University, East Lansing, Michigan, USA
^bDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA
^cCenter for Microbiome Innovation, University of California San Diego, La Jolla, California, USA
^dJacobs School of Engineering, University of California San Diego, La Jolla, California, USA
^eDivision of Biostatistics, University of California San Diego, La Jolla, California, USA
^fCenter for Computational Biology, Flatiron Institute, Simons Foundation, New York, New York, USA
^gDepartment of Medicine, University of California San Diego, La Jolla, California, USA
^hDepartment of Computer Science and Engineering and Bioengineering, University of California San Diego, La Jolla, California, USA
ⁱSkaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA

Address correspondence to Douglas Conrad (clinical aspects), dconrad{at}ucsd.edu, Rob Knight (sequencing), rknight{at}ucsd.edu, Pieter C. Dorrestein (mass spectrometry), pdorrestein{at}ucsd.edu, or Robert A. Quinn (study design and analysis), quinnrob{at}msu.edu.
↵* Present address: Karla Vasco, Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.
Ruma Raghuvanshi and Karla Vasco contributed equally to this work as co-first authors. Author order was determined alphabetically by last name.
Citation Raghuvanshi R, Vasco K, Vázquez-Baeza Y, Jiang L, Morton JT, Li D, Gonzalez A, DeRight Goldasich L, Humphrey G, Ackermann G, Swafford AD, Conrad D, Knight R, Dorrestein PC, Quinn RA. 2020. High-resolution longitudinal dynamics of the cystic fibrosis sputum microbiome and metabolome through antibiotic therapy. mSystems 5:e00292-20. https://doi.org/10.1128/mSystems.00292-20.