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Special Issue Perspective | Synthetic Biology

Toward Autonomous Antibiotic Discovery

Cesar de la Fuente-Nunez
Cesar de la Fuente-Nunez
aMachine Biology Group, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
bDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
cDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA
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DOI: 10.1128/mSystems.00151-19
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Article Information

DOI 
https://doi.org/10.1128/mSystems.00151-19
PubMed 
31186311

Published By 
American Society for Microbiology Journals
History 
  • Received February 27, 2019
  • Accepted May 10, 2019
  • Published online June 11, 2019.

Copyright & Usage 
Copyright © 2019 de la Fuente-Nunez. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Author Information

  1. Cesar de la Fuente-Nuneza,b,c
  1. aMachine Biology Group, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
  2. bDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
  3. cDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA
  • Address correspondence to cfuente{at}pennmedicine.upenn.edu.
  • Conflict of Interest Disclosures: C.D.L.F.-N. has two patents, case no. 20320J and 20758, pending from MIT.

  • Citation de la Fuente-Nunez C. 2019. Toward autonomous antibiotic discovery. mSystems 4:e00151-19. https://doi.org/10.1128/mSystems.00151-19.

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Toward Autonomous Antibiotic Discovery
Cesar de la Fuente-Nunez
mSystems Jun 2019, 4 (3) e00151-19; DOI: 10.1128/mSystems.00151-19

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Toward Autonomous Antibiotic Discovery
Cesar de la Fuente-Nunez
mSystems Jun 2019, 4 (3) e00151-19; DOI: 10.1128/mSystems.00151-19
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  • Top
  • Article
    • ABSTRACT
    • PERSPECTIVE
    • THE ANTIBIOTIC RESISTANCE PROBLEM
    • THE END OF NATURE AS AN ANTIBIOTIC GENERATOR
    • COMPUTER-MADE ARTIFICIAL ANTIBIOTICS
    • PATTERN RECOGNITION-DRIVEN DISCOVERY
    • THE FUTURE OF ANTIBIOTIC DISCOVERY
    • ACKNOWLEDGMENTS
    • FOOTNOTES
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • PDF

KEYWORDS

computer-made drugs
antibiotic discovery
antimicrobial resistance
machines

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