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Special Issue Perspective | Novel Systems Biology Techniques

Computational Genomics of Specialized Metabolism: from Natural Product Discovery to Microbiome Ecology

Marnix H. Medema
Marnix H. Medema
aBioinformatics Group, Wageningen University, Wageningen, The Netherlands
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DOI: 10.1128/mSystems.00182-17
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Article Information

DOI 
https://doi.org/10.1128/mSystems.00182-17

Published By 
American Society for Microbiology Journals
History 
  • Received November 9, 2017
  • Accepted November 23, 2017
  • Published online March 6, 2018.

Copyright & Usage 
Copyright © 2018 Medema. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

Author Information

  1. Marnix H. Medemaa
  1. aBioinformatics Group, Wageningen University, Wageningen, The Netherlands
  • Address correspondence to marnix.medema{at}wur.nl.
  • ↵Conflict of Interest Disclosures: M.H.M. reports grants from NWO, ZonMW, the NIH, and the Graduate School for Experimental Plant Sciences during the conduct of the study, in addition to personal fees from Hexagon Bio and Third Rock Ventures outside the submitted work.

  • Citation Medema MH. 2018. Computational genomics of specialized metabolism: from natural product discovery to microbiome ecology. mSystems 3:e00182-17. https://doi.org/10.1128/mSystems.00182-17.

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Computational Genomics of Specialized Metabolism: from Natural Product Discovery to Microbiome Ecology
Marnix H. Medema
mSystems Mar 2018, 3 (2) e00182-17; DOI: 10.1128/mSystems.00182-17

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Computational Genomics of Specialized Metabolism: from Natural Product Discovery to Microbiome Ecology
Marnix H. Medema
mSystems Mar 2018, 3 (2) e00182-17; DOI: 10.1128/mSystems.00182-17
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  • Top
  • Article
    • ABSTRACT
    • PERSPECTIVE
    • FROM INDIVIDUAL GENOMES TO PANGENOMES AND METAGENOMES
    • CONNECTING GCFs TO MOLECULES
    • CONNECTING MICROBES TO PLANT AND HUMAN HOSTS
    • ACKNOWLEDGMENTS
    • FOOTNOTES
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • PDF

KEYWORDS

bioinformatics
biosynthetic gene cluster
microbiome
natural products
specialized metabolism

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