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Research Article | Host-Microbe Biology

Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice

Thomas Sharpton, Svetlana Lyalina, Julie Luong, Joey Pham, Emily M. Deal, Courtney Armour, Christopher Gaulke, Shomyseh Sanjabi, Katherine S. Pollard
Jack A. Gilbert, Editor
Thomas Sharpton
a Department of Microbiology, Oregon State University, Corvallis, Oregon
b Department of Statistics, Oregon State University, Corvallis, Oregon
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Svetlana Lyalina
c Gladstone Institutes, San Francisco, California, USA
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Julie Luong
c Gladstone Institutes, San Francisco, California, USA
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Joey Pham
c Gladstone Institutes, San Francisco, California, USA
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Emily M. Deal
c Gladstone Institutes, San Francisco, California, USA
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Courtney Armour
a Department of Microbiology, Oregon State University, Corvallis, Oregon
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Christopher Gaulke
a Department of Microbiology, Oregon State University, Corvallis, Oregon
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Shomyseh Sanjabi
c Gladstone Institutes, San Francisco, California, USA
d Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, California, USA
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Katherine S. Pollard
c Gladstone Institutes, San Francisco, California, USA
e Department of Epidemiology & Biostatistics, Institute for Human Genetics, and Institute for Computational Health Sciences, University of California, San Francisco, San Francisco, California, USA
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Jack A. Gilbert
University of Chicago
Roles: Editor
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DOI: 10.1128/mSystems.00036-17
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Article Information

DOI 
https://doi.org/10.1128/mSystems.00036-17
PubMed 
28904997

Published By 
American Society for Microbiology Journals
History 
  • Received May 4, 2017
  • Accepted August 8, 2017
  • Published online September 5, 2017.

Copyright & Usage 
Copyright © 2017 Sharpton et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license .
Editors and / or Reviewers 
  • Jack A. Gilbert, Editor, University of Chicago

Author Information

  1. Thomas Sharptona,b,
  2. Svetlana Lyalinac,
  3. Julie Luongc,
  4. Joey Phamc,
  5. Emily M. Dealc,
  6. Courtney Armoura,
  7. Christopher Gaulkea,
  8. Shomyseh Sanjabic,d and
  9. Katherine S. Pollardc,e
  1. a Department of Microbiology, Oregon State University, Corvallis, Oregon
  2. b Department of Statistics, Oregon State University, Corvallis, Oregon
  3. c Gladstone Institutes, San Francisco, California, USA
  4. d Department of Microbiology & Immunology, University of California, San Francisco, San Francisco, California, USA
  5. e Department of Epidemiology & Biostatistics, Institute for Human Genetics, and Institute for Computational Health Sciences, University of California, San Francisco, San Francisco, California, USA
  • Address correspondence to Katherine S. Pollard, kpollard{at}gladstone.ucsf.edu.
  • T.S. and S.L. contributed equally to this article.

  • Citation Sharpton T, Lyalina S, Luong J, Pham J, Deal EM, Armour C, Gaulke C, Sanjabi S, Pollard KS. 2017. Development of inflammatory bowel disease is linked to a longitudinal restructuring of the gut metagenome in mice. mSystems 2:e00036-17. https://doi.org/10.1128/mSystems.00036-17 .

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Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice
Thomas Sharpton, Svetlana Lyalina, Julie Luong, Joey Pham, Emily M. Deal, Courtney Armour, Christopher Gaulke, Shomyseh Sanjabi, Katherine S. Pollard
mSystems Sep 2017, 2 (5) e00036-17; DOI: 10.1128/mSystems.00036-17

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Development of Inflammatory Bowel Disease Is Linked to a Longitudinal Restructuring of the Gut Metagenome in Mice
Thomas Sharpton, Svetlana Lyalina, Julie Luong, Joey Pham, Emily M. Deal, Courtney Armour, Christopher Gaulke, Shomyseh Sanjabi, Katherine S. Pollard
mSystems Sep 2017, 2 (5) e00036-17; DOI: 10.1128/mSystems.00036-17
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KEYWORDS

inflammatory bowel disease
lipooligosaccharide transporter
longitudinal
metagenomics
protein function
statistics

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