Latest Articles
Research ArticleSpinal Cord Injury Changes the Structure and Functional Potential of Gut Bacterial and Viral CommunitiesTo our knowledge, this is the first article to apply metagenomics to characterize changes in gut microbial population dynamics caused by a clinically relevant model of central nervous system (CNS) trauma. It also utilizes the most current approaches in genome-resolved metagenomics and viromics to maximize the biological inferences that can be made from these data.
Research ArticleMycobacteria Tolerate Carbon Monoxide by Remodeling Their Respiratory ChainCarbon monoxide has an infamous reputation as a toxic gas, and it has been suggested that it has potential as an antibacterial agent. Despite this, how bacteria resist its toxic effects is not well understood.
Research ArticleBradyrhizobium diazoefficiens USDA110 Nodulation of Aeschynomene afraspera Is Associated with Atypical Terminal Bacteroid Differentiation and Suboptimal Symbiotic EfficiencyLegume-rhizobium symbiosis is a major ecological process in the nitrogen cycle, responsible for the main input of fixed nitrogen into the biosphere. The efficiency of this symbiosis relies on the coevolution of the partners.
Research ArticleInterkingdom Gut Microbiome and Resistome of the Cockroach Blattella germanicaFor the first time, we analyze the interkingdom hindgut microbiome of this species, including bacteria, fungi, archaea, and viruses. Network analysis reveals putative cooperation between core bacteria that could be key for ecosystem equilibrium.
Research ArticleFreshwater Chlorobia Exhibit Metabolic Specialization among Cosmopolitan and Endemic PopulationsThe reconstruction of genomes from metagenomes has helped explore the ecology and evolution of environmental microbiota. We applied this approach to 274 metagenomes collected from diverse freshwater habitats that spanned oxic and anoxic zones, sampling seasons, and latitudes.
Research ArticleIdentification of c-di-GMP/FleQ-Regulated New Target Genes, Including cyaA, Encoding Adenylate Cyclase, in Pseudomonas putidac-di-GMP/FleQ promotes the plankton-to-biofilm lifestyle transition at the transcriptional level via FleQ in Pseudomonas species. Identification of new target genes directly regulated by c-di-GMP/FleQ helps to broaden the knowledge of c-di-GMP/FleQ-mediated transcriptional regulation.
Research ArticleMetagenomics and Quantitative Stable Isotope Probing Offer Insights into Metabolism of Polycyclic Aromatic Hydrocarbon Degraders in Chronically Polluted SeawaterOil spills in the marine environment have a devastating effect on marine life and biogeochemical cycles through bioaccumulation of toxic hydrocarbons and oxygen depletion by hydrocarbon-degrading bacteria. Oil-degrading bacteria occur naturally in the ocean, especially where they are supported by chronic inputs of oil or other organic carbon sources, and have a significant role in degradation of oil spills.
Research ArticleOral Epithelial Cells Distinguish between Candida Species with High or Low Pathogenic Potential through MicroRNA RegulationA relatively new topic within the field of immunology involves the role of miRNAs in innate as well as adaptive immune response regulation. In recent years, posttranscriptional regulation of host-pathogenic fungal interactions through miRNAs was also suggested.
Research ArticleRapid Response of Nitrogen Cycling Gene Transcription to Labile Carbon Amendments in a Soil Microbial CommunityA large portion of activity in soil microbial communities occurs in short time frames in response to an increase in C availability, affecting the biogeochemical cycling of nitrogen. These changes are of particular importance as nitrogen represents both a limiting nutrient for terrestrial plants as well as a potential pollutant.
Research ArticleQuantitative Proteomics Reveals that Hsp90 Inhibition Dynamically Regulates Global Protein Synthesis in Leishmania mexicanaLeishmania spp. are the causative agents of leishmaniasis, a poverty-related disease, which is endemic in >90 countries worldwide, affecting approximately 12 million people, with an estimated 700,000 to 1 million new cases and around 70,000 deaths annually. Inhibitors of the chaperone protein Hsp90 have shown promising antileishmanial activity.
About mSystems
mSystems®, an open access journal from the American Society for Microbiology, publishes the best research in single-cell and community microbial systems biology, new computational and laboratory approaches, and synthetic biology.
For Authors
mSystems Podcast: New Episode
Pandemic Built Environment: a conversation with Prof. Leslie Dietz, Prof. Patrick Horve, and Prof. Kevin Van Den Wymelenberg. Hosted by mSystems Editor in Chief Dr. Jack A. Gilbert.
Author Video Summaries
Watch an author summary of "Molecular and Physiological Adaptations to Low Temperature in Thioalkalivibrio Strains Isolated from Soda Lakes with Different Temperature Regimes" and read the article.
